The chemical structure of compounds is one of the basic characteristics which a scientist needs to know to further predict its properties and its interaction with other substances, light, and its probability as a potential drug candidate. In the second half of the last century, spectroscopic techniques have flourished so much that scientists and researchers are using them efficiently as a tool for structure determination of compounds. The most frequently used spectroscopic techniques for this purpose are UV/visible, Infrared (IR), Nuclear Magnetic Resonance (NMR), and Mas Spectrometry (MS). Each technique furnishes different information about the structure of the compounds, which may be combined to get to the final structure. Let’s see how useful these techniques are.