Is Stereoselectivity a problem? Try Enzymes

Stereoselectivity is a major issue in synthetic organic chemistry. The use of chiral reagents and catalysts can solve the problem to a greater extent. But there are problems associated with the use of these chemicals as they may be expensive, hard to get, and most of the time not friendly for the environment. Enzymes, the biological catalysts, have been used as chiral catalysts for carrying out stereoselective reactions, mainly because of their specific nature. Enzymes are proven to be environmentally benign.

Protein Microchips: A New Era of Drug Discovery, Biocatalysis and Diagnosis

 

Over the last decade or so, the field of drug discovery, diagnosis, high-throughput screening, and biochemical analyses have been revolutionized with the discovery of modern and sophisticated instruments and new technologies. Protein microchips is one of them.

Chemistry of Life: From Fertilization to Death

Human life starts with the fertilization of sperm with egg and ends when all the body functions cease to work. This whole time span is a complex combination of chemical reactions and processes, taking place frequently and continuously. A very important thing to be kept in mind before reading the article is that the terms steroids, carbohydrates, lipids, proteins, enzymes, hormones, DNA, RNA etc., wherever used in the article, are all chemical compounds or macromolecules composed of chemical entities, in other words, it’s all about chemistry.

SIGNAL GENERATION IN NMR

  

We know that a spin active nucleus behaves as a tiny magnet under the influence of a strong magnetic field. Such nuclei have an intrinsic property of arranging themselves in all possible spin states in the presence of a magnetic field. The possible spin states can be calculated from the spin quantum number.

PRINCIPLE OF NMR SPECTROSCOPY

 

Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique employed for various analytical purposes, especially structural characterization of organic compounds.

NMR deals with the behavior of nucleus under the influence of a strong magnetic field and absorption of radiofrequency. Not all nuclei can be studied in NMR.

Woodward Fieser Rules for Enones and Benzophenones

Woodward Fieser Rules can be applied to enones and benzophenones as well, for calculating their wavelength of maximum absorption.

Woodward Fieser Rules for Dienes (With subtitles) | Examples | UV/Vis Sp...

Woodward Fieser Rules for dienes help in calculating wavelength for maximum absorption. In most cases, the calculated value conforms with the observed value.